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Variety.com

Script analysis company says computers can be more successful than humans in greenlighting projects

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According to the founder of artificial intelligence outfit ScriptBook , cheap 2014 recommend sale online Prada Suede Wedge Slide Sandals 2014 unisex online 2UwFamDoC
could have saved a fortune from 2015 to 2017 by using the company’s algorithms instead of human beings to reject or greenlight movies.

In a presentation at the Karlovy Vary Intl. Film Festival, ScriptBook founder Nadira Azermai said that by analyzing screenplays, ScriptBook retroactively identified as box-office failures 22 out of the 32 Sony movies that lost money in that period, during which Sony released a total of 62 movies.

“If Sony had used our system they could have eliminated 22 movies that failed financially,” said Azermai.

Welcome to the brave new world of AI and machine learning as it applies to Hollywood.

Many see in ScriptBook and similar AI systems the potential to destroy a major part of the film production and distribution ecosystem, displacing script readers and saving much of the money studios spend on test screenings, focus groups and market research.

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At its most basic, ScriptBook, founded in 2015 and based in Antwerp, Belgium, has created a tool that analyzes the text of screenplays to produce financial forecasting, or as Azermai grandly puts it, “Our mission is to revolutionize the business of storytelling by using AI to help producers, distributors, sales agents and financiers assess their risk.”

The cloud-based system is already in use. In 2016 ScriptBook raised $1.4 million in venture capital to accelerate development.

The system works like this: ScriptBook users upload a PDF file of a screenplay into the system. About five minutes later they receive a detailed analysis of the project that, among other things: predicts the MPAA rating, analyzes its characters, detecting the protagonists and antagonists; assesses the emotions of each character; predicts the target audience, including gender and race; and, most importantly, makes box office predictions.

“When we show this to customers, the first question is: How is it even possible to give a script to a computer and somehow it can come up with all these outputs?” said Michiel Ruelens, data scientist at Scriptbook.

The answer, he says, is based on the fast-developing field of machine learning, whereby the software is first instructed by humans, then takes over the learning process and builds huge databases that can be mined at astonishing speed.

Beta blockers can precipitate or exacerbate heart failure. Despite this potential, subgroup analysis of randomized controlled trials has shown that patients with heart failure derive greater benefit from beta blockers following myocardial infarction than patients without heart failure. Rebecca Minkoff Leather RoundToe Flats genuine 4jA4lxpB
In the BHAT, 22 propranolol reduced mortality equally, by approximately 25 percent, in patients with and without heart failure. However, beta-blocker therapy was associated with a 47 percent reduction in sudden death in patients with heart failure, compared with a 13 percent reduction in patients without heart failure.

Recent studies have shown that beta blockers are often beneficial in the treatment of chronic heart failure. Two meta-analyses of randomized trials reported a reduction in mortality of approximately 30 percent in patients with heart failure who received beta blockers. Paul Andrew Zenadia PointedToe Pumps discount big sale sale authentic cheap hot sale buy cheap sneakernews genuine cheap online M7OCGh
, 24 Carvedilol (Coreg) was labeled by the U.S. Food and Drug Administration for the treatment of mild to moderate heart failure after publication of a large randomized trial that demonstrated a 65 percent mortality reduction in patients who received this agent. 25 Subsequently, studies of the beta blockers bisoprolol 26 and metoprolol Marni Snakeskin Mary Jane Pumps best seller for sale cheap sale in China outlet explore Xpd3NWN
in the treatment of heart failure were terminated early when reductions of 34 percent in all-cause mortality and 40 to 45 percent in sudden death were demonstrated. It should be kept in mind that beta blockers were added in these studies after treatment had been optimized with diuretics, angiotensin-converting enzyme (ACE) inhibitors and, in some cases, digoxin. Furthermore, despite promising preliminary data, the efficacy and safety of beta blockers in patients with New York Heart Association (NYHA) class IV heart failure remains uncertain. 28

Clinical evidence clearly shows that beta blockers are beneficial after myocardial infarction in most patients, including those with reduced left ventricular function or heart failure. In patients with heart failure, beta-blocker therapy should be started at the lowest dosage and slowly titrated upward. A transient worsening of the symptoms of heart failure may occur before significant improvement is seen. Beta blockers should be withheld in patients with severe or decompensated heart failure, until the patient's condition is stabilized with diuretic and ACE inhibitor therapy.

Beta blockers, particularly nonselective agents, have been shown to increase the serum triglyceride level and lower the high-density lipoprotein (HDL) cholesterol level. Pierre Hardy Leather Ankle Strap Sandals clearance outlet locations clearance best seller free shipping clearance store brand new unisex discount cheap F4a4LzTiqc
Other pharmacologic effects of beta blockers, however, may actually impede the development of atherosclerosis and thrombogenesis. 29 The overall clinical importance of the lipid-modifying effects of beta blockers remains unclear. Lipid abnormalities should be treated but are not a justification for withholding beta-blocker therapy after myocardial infarction.

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